Medicinal Chemist (Scientist Level)

Jnana Therapeutics is an exciting new startup focused on drugging the SLC family of metabolite transporters using a novel drug discovery platform. The company is focused on gut and immunometabolism, as well as lysosomal and mitochondrial function – important disease pathways where SLC transporters provide novel targets for inflammatory disorders, immuno-oncology, and neurological diseases.

At Jnana, we are passionate about leaving a legacy of healthy people, who as a result of breakthrough medicines lead transformed lives. We are building a company committed to innovative science, rigorous drug development, and a constant appreciation for the privilege to serve society by developing medicines. A bold team empowered to perform beyond traditional roles is at the center of all we do. We are seeking individuals who are inspired by this vision.

Role:

 Jnana Therapeutics is seeking an enthusiastic and highly motivated Medicinal Chemist to join our expanding team.  This individual will use both traditional and parallel synthesis techniques to impact projects at all stages of discovery and development, and will be involved in the design and synthesis of tool molecules and chemical probes to further our understanding of SLC biology.

Responsibilities:

  • Engage in medicinal chemistry projects targeting SLCs of interest in collaboration with experienced medicinal chemists

  • Design and synthesis of small molecule modulators of SLC function

  • Design and synthesis of tool compounds and molecular probes to enable chemical biology target exploration

  • Interpret and analyze data using a range of software tools and computational approaches

  • Closely collaborate with colleagues, internal and external, in multiple scientific disciplines across R&D

  • Help to build and expand an innovative chemical biology platform for drug discovery 

Qualifications and Skills:

  • Ph.D. in synthetic organic chemistry required, with + 1-5yr post-doctoral and/or industrial experience desirable

  • Expertise in modern synthetic methodologies and analytical techniques

  • Exemplary lab-based innovator

  • Eagerness to contribute in the hood

  • Familiarity with parallel synthesis and purification an advantage, but not required

  • Collaborative researcher with strong teamworking skills

  • Desire to contribute insights outside of core expertise

  • Ability to adapt to frequent change and thrive in a dynamic and entrepreneurial early-stage environment