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Senior Scientist / Principal Scientist (Cellular Assay Development Scientist)

Jnana Therapeutics is a biotechnology company utilizing a next generation chemoproteomic platform to address well-validated but hard-to-drug targets, including the solute carrier (SLC) family of metabolite transporters. Jnana is focused on developing best-in-class therapies to treat a wide range of diseases, including immune-mediated, neurological and metabolite-dependent diseases. Headquartered in Boston, Jnana is founded by world-renowned scientists and backed by leading life science investors. For more information, please visit and follow us on Twitter and on LinkedIn.


Jnana therapeutics is seeking a molecular and cell biology specialist to help drive the expansion of our portfolio. The ideal candidate has a proven track record of engineering cell lines and developing novel cell-based assays that they then leverage to execute small-molecule or genetic screens.

You are scientifically curious, treat opportunity and challenges with equal vigor and contribute beyond your precise role description.  This is an outstanding opportunity for a passionate scientist to apply their drug hunting skills while contributing to bringing new classes of medicines to patients.


  • You will translate exciting new target concepts into bona fide drug discovery programs through the expert design and development of a cascade of cell-based assays that enable functional characterization of small molecule binders arising from our RAPID
  • Mentoring junior research scientists
  • Regular presentations of your data to colleagues and leadership.


  • PhD in Cell Biology or a relevant discipline with 5 years of independent research experience in academia or industry, or BS/MS with 10 years of industry experience.
  • Well-versed in vector selection, construct design/engineering, and a range of gene delivery technologies (transfection, transduction, electroporation, CRISPR knock-in).
  • Hands-on experience overcoming challenges in cell line engineering and assay development to enable the subsequent execution of a medium- or high-throughput screen is a must.
  • Experience with mentoring and developing others.
  • Hands-on experience with liquid handling instrumentation (Tecan, Viaflo, Biotek) is a plus.

To apply, please email [email protected] or fill out the form directly through our website.


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