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Immunologist (Principal Scientist Level)

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Jnana Therapeutics is an exciting new startup focused on drugging the SLC family of metabolite transporters using a novel drug discovery platform. The company is focused on gut and immunometabolism, as well as lysosomal and mitochondrial function – important disease pathways where SLC transporters provide novel targets for inflammatory disorders, immuno-oncology, and neurological diseases.

At Jnana, we are passionate about leaving a legacy of healthy people, who as a result of breakthrough medicines lead transformed lives. We are building a company committed to innovative science, rigorous drug development, and a constant appreciation for the privilege to serve society by developing medicines. A bold team empowered to perform beyond traditional roles is at the center of all we do. We are seeking individuals who are inspired by this vision.

Role:

The successful candidate will have a deep knowledge of immunology and significant experience with cellular assays in immune cells, with a particular focus on innate immunity. This role requires a self-starter with a Pharma or Biotech track record working and leading projects focused on macrophage or dendritic cell biology in autoimmune or inflammatory diseases, or immuno-oncology. Knowledge of and experience in immunometabolism or disease pathways involved in inflammatory bowel disease would be especially useful.

Responsibilities:

  • Responsibility for the development and validation of in vitro and ex vivo immunoassays to evaluate innate immune cell function
  • Ability to generate and experimentally validate potential target hypotheses, with a deep mechanistic understanding of the target in disease pathways of interest
  • Presentation of results to the team, leadership, and Board members regularly with full transparency
  • Using excellent scientific and personal communication skills to work cross-functionally internally and externally with collaborators
  • Deep knowledge of the scientific literature, attendance at scientific conferences, and application of external insights to internal drug discovery programs

Qualifications and Skills:

  • PhD in Immunology with 7+ years of drug discovery Industry experience
  • Expertise with innate immune cell biology and functional assays, particularly macrophage and/or dendritic cell biology
  • Proficiency with immune cell assay technologies including flow cytometry, FACS analysis, and screens involving small molecules and/or genetic perturbations (e.g. CRISPR)
  • Collaborative researcher with strong teamworking skills
  • Desire to contribute insights outside of core expertise
  • Ability to adapt to frequent change and thrive in a dynamic and entrepreneurial early-stage environment

To apply, please email jobs@jnanatx.com or fill out the form directly through our website.

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