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Director, Biology

Jnana Therapeutics is a biotechnology company focused on modulating cellular metabolism by opening the solute carrier (SLC) family of metabolite transporters as a target class to develop transformational therapeutics. Jnana uses RAPID, its proprietary, cell-based drug discovery platform to systematically target SLC transporters and develop best-in-class therapies to treat a wide range of diseases, including immune-mediated, neurological and metabolite-dependent diseases. Headquartered in Boston, Jnana is founded by world-renowned scientists and backed by leading life science investors. For more information, please visit www.jnanatx.com and follow us on Twitter and on LinkedIn.

POSITION DESCRIPTION

Jnana Therapeutics is seeking a Biopharma industry accomplished Biologist to help advance drug discovery programs focused on SLC targets which play a role in metabolite-dependent diseases. Such targets demonstrate a strong human biology link between the SLC and its associated metabolite in the selected disease, as well as a clear translational path to patient selection and demonstration of clinical efficacy. An ideal candidate will possess a deep and mechanistic knowledge of cellular biology applied to cell assay development and use in target validation and assessment of target or pathway modulators. Significant experience in prosecuting discovery programs from target selection and validation through development candidate identification and early translational development is essential. Providing guidance to project teams in developing and executing on scientific and program strategies is critical. A detailed understanding of cellular metabolism is preferred. At Jnana, we are committed to team and mission, so we seek out leaders who have a track record of dedication, curiosity, and productive collaboration.

RESPONSIBILITIES

  • Serve as an integral member of the Biology team, focused on initiating and prosecuting SLC Drug Discovery programs through identification of development candidates and preclinical studies.
  • Collaborate with Discovery Chemistry and Biology colleagues to propose and execute on program strategy, including assay/model development.
  • Work with translational scientists to formulate biomarker and patient selection strategy across multiple projects.
  • Propose novel targets for drug discovery programs
  • Interface with senior leadership and partner organizations as appropriate to communicate results and set strategy.
  • Maintain expertise of the scientific literature and apply target biology insights across drug discovery programs.
  • Maintain a safe and productive laboratory environment, mentor and train research associates and scientists
  • Contribute intellectually to and help drive scientific discussions, meetings, and presentations.
  • Help build and expand an innovative platform for drug discovery.

QUALIFICATIONS

  • Ph.D. in Cell Biology or Biochemistry with 8+ years’ experience in the Biopharma industry.
  • Proven track record in drug discovery and development, preferentially with small molecules.
  • Experience in multiple therapeutic areas is preferred, with specific preference for Renal and/or Rare diseases.
  • Track record of mentorship and leadership.

 

HOW TO APPLY

To apply, please email [email protected] or fill out the form directly through our website.

 

 

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